VcMMAE-Eribulin
VcMMAE-Eribulin is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule MMAE (HY-15162) (Microtubule inhibitor) and Eribulin (HY-13442) (Microtubule inhibitor) . VcMMAE-Eribulin can be used for ADC synthesis.
Product Specifications
CAS Number
[2760408-69-1]
Product Name Alternative
SMP13432
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vcmmae-eribulin.html
Purity
98.87
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C=C1C[C@@]2([H])O[C@@]1([H])CC[C@]3([H])O[C@](C([C@H](C)C3)=C)([H])C[C@@]4([H])[C@]([C@@H](OC)[C@@H](C[C@H](O)CNC(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CC(C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC6=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N7[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C8=CC=CC=C8)=O)([H])CCC7)=O)C)=O)=O)=O)C=C6)=O)=O)=O)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)=O)=O)C=C5)=O)O4)([H])CC(C[C@]%10([H])O[C@]%11([H])[C@]%12([H])O[C@@]%13(O[C@@]%14([H])[C@@](O[C@]%12([H])[C@@]%14([H])O[C@@]%11([H])CC%10)([H])C%13)CC2)=O
Molecular Formula
C131H194N18O33
Molecular Weight
2549.04
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Dual payloads
Available Sizes
Curated Selection
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