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Gatipotuzumab

Product Specifications

UNSPSC Description

Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC)[1][2].

Target Antigen

Mucin

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gatipotuzumab.html

Purity

95.0

Solubility

H2O

Smiles

[Gatipotuzumab]

References & Citations

[1]Macchini M, et al. Results from the primary analysis of a 30 patient extension of the GATTO study, a phase Ib study combining the anti-MUC1 gatipotuzumab (GAT) with the anti-EGFR tomuzotuximab (TO) or panitumumab in patients with refractory solid tumors. European Journal of Cancer, 2020, 138: S5-S6.|[2]Danielczyk A, et al. PankoMab: a potent new generation anti-tumour MUC1 antibody. Cancer Immunol Immunother. 2006 Nov;55(11):1337-47.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99634/Gatipotuzumab-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99634/Gatipotuzumab-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

1264737-26-9

Available Sizes

Curated Selection

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