Clofibric acid
Product Specifications
UNSPSC Description
Clofibric acid (Chlorofibrinic acid), the pharmaceutically active metabolite of lipid regulators Clofibrate, Etofibrate and Etofyllinclofibrate, is a PPARα agonist which exhibits hypolipidemic effects. Clofibric acid also is an herbicide[1][2][3].
Target Antigen
Drug Metabolite; PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Clofibric-acid.html
Purity
99.99
Solubility
DMSO : ≥ 100 mg/mL|H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C)
Smiles
CC(C)(OC1=CC=C(Cl)C=C1)C(O)=O
Molecular Weight
214.648
References & Citations
[1]Forman BM, et, al. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4312-7.|[2]Salgado R, et, al. Biodegradation of clofibric acid and identification of its metabolites. J Hazard Mater. 2012 Nov 30;241-242:182-9.|[3]Kawashima Y, et, al. Increased activity of stearoyl-CoA desaturation in liver from rat fed clofibric acid. Biochim Biophys Acta. 1982 Dec 13;713(3):622-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1415/Clofibric-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1415/Clofibric-acid-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
882-09-7
Available Sizes
Curated Selection
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