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Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9)

Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived IgG2a κ type antibody inhibitor targeting to mouse CTLA-4/CD152. Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) contains a LALA-PG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) can be used for the researches of cancer and immunology, such as colon[1][2].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

CTLA-4

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-ctla-4-cd152-lala-pg-antibody-9d9.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCTLA-4/CD152(LALA-PG)Antibody(9D9)]

Molecular Weight

(150 kDa)

References & Citations

[1]Wing JB, et al. Regulatory T cells control antigen-specific expansion of Tfh cell number and humoral immune responses via the coreceptor CTLA-4. Immunity. 2014 Dec 18;41 (6) :1013-25.|[2]Bulliard Y, et al. Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. J Exp Med. 2013 Aug 26;210 (9) :1685-93.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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