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Lovastatin hydroxy acid (sodium)

Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM[1].

Product Specifications

CAS Number

[75225-50-2]

Product Name Alternative

Mevinolinic acid (sodium)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

HMG-CoA Reductase (HMGCR)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/lovastatin-hydroxy-acid-sodium.html

Purity

99.50

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C[C@@H](C[C@@H](CC[C@H]1[C@H](C=CC2=C[C@@H](C[C@@H]([C@]12[H])OC([C@H](CC)C)=O)C)C)O)O)O[Na]

Molecular Formula

C24H37NaO6

Molecular Weight

444.54

Precautions

H302, H315, H319, H335

References & Citations

[1]A W Alberts, eta al. Mevinolin: A Highly Potent Competitive Inhibitor of Hydroxymethylglutaryl-Coenzyme A Reductase and a Cholesterol-Lowering Agent. Proc Natl Acad Sci U S A. 1980 Jul;77 (7) :3957-61.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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