Diclofenac (Standard)
Diclofenac (Standard) is the analytical standard of Diclofenac. This product is intended for research and analytical applications. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
Product Specifications
CAS Number
15307-86-5
UNSPSC
12352005
Hazard Statement
H301, H361, H372, H411
Target
Apoptosis; COX; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/diclofenac-standard.html
Purity
99.91
Smiles
O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl
Molecular Formula
C14H11Cl2NO2
Molecular Weight
296.15
Precautions
H301, H361, H372, H411
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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