Avenanthramide C

Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β (Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimer’s disease[1].

Product Specifications

CAS Number

[116764-15-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/avenanthramide-c.html

Purity

98.90

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(O)=CC=C1NC(/C=C/C2=CC=C(C(O)=C2)O)=O)O

Molecular Formula

C16H13NO6

Molecular Weight

315.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Matsukawa T, et al. Occurrence of avenanthramides and hydroxycinnamoyl-CoA:hydroxyanthranilate N-hydroxycinnamoyltransferase activity in oat seeds. Z Naturforsch C J Biosci. 2000 Jan-Feb;55 (1-2) :30-6. |[2]Ramasamy VS, et al. Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice. Mol Neurobiol. 2020 Jan;57 (1) :315-330.Ramasamy VS, et al. Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice. Mol Neurobiol. 2020 Jan;57 (1) :315-330.