Avenanthramide C
Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β (Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimer’s disease[1].
Product Specifications
CAS Number
116764-15-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/avenanthramide-c.html
Purity
98.90
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(O)=CC=C1NC(/C=C/C2=CC=C(C(O)=C2)O)=O)O
Molecular Formula
C16H13NO6
Molecular Weight
315.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Matsukawa T, et al. Occurrence of avenanthramides and hydroxycinnamoyl-CoA:hydroxyanthranilate N-hydroxycinnamoyltransferase activity in oat seeds. Z Naturforsch C J Biosci. 2000 Jan-Feb;55 (1-2) :30-6. |[2]Ramasamy VS, et al. Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice. Mol Neurobiol. 2020 Jan;57 (1) :315-330.Ramasamy VS, et al. Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice. Mol Neurobiol. 2020 Jan;57 (1) :315-330.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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