Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

4-Hydroxy-2-hexenal Antibody: FITC

Mouse Anti-4-Hydroxy-2-hexenal Monoclonal IgG1

Product Specifications

Background

Lipid peroxidation occurs when oxidizing agents attack carbon-carbon double bonds found in unsaturated lipids. In addition to membrane degradation, oxidation end-products have been found to damage cell viability through their mutagenic and toxic properties. These downstream functional consequences facilitate the development of disease and premature aging. 4-hydroxy-2-hexenal (4-HHE) is a major alpha,beta-unsaturated aldehyde product of n-3 PUFA oxidation resulting from lipid peroxidation. High levels of HHE are found in disease states (1). 4-HHE reacts with histidine residues to form Michael-addition type adducts.

Specifications

Specific for 4-Hydroxy-2-hexenal. Slight cross-reactivity with 4-Hydroxynonenal. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, Malondialdehyde, or Methylglyoxal modified proteins.

Product Name Alternative

4-Hydroxy-2-hexenal (4-HHE) Antibody, 4-Hydroxy-2-hexenal Antibody, 4-HHE Antibody, MG Antibody, MG-modified protein Antibody, 4-Hydroxy-2-hexenal-modified , 4-Hydroxy-2-hexenal Antibody, 4-hydroxy Hexenal Antibody, HHE Antibody, 4-HHE Antibody

Synonyms

4-Hydroxy-2-hexenal Antibody, Clone 5C11.1: FITC

UNSPSC

12352203

Host

Mouse

Species Reactivity

Species Independent

Immunogen

Synthetic 4-Hydroxy-2-hexenal modified Keyhole Limpet Hemocyanin (KLH)

Target

4-Hydroxy-2-hexenal

Clonality

Monoclonal

Isotype

IgG1

Clone

5C11.1

Conjugation

FITC

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

A 1:1000 dilution of SMC-536 was sufficient for detection of 4-Hydroxy-2-hexenal in 1 µg of 4-Hydroxy-2-hexenal-BSA conjugate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Concentration

1 mg/ml

Dilution

WB (1:1000); ELISA (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Long, EK., Picklo, MJ Sr. (2010) Free Radic Biol Med. 49(1):1-8.

Product Datasheet

https://cdn.gentaur.com/products/400/4293663/datasheet/smc-536d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/4293663/msds/smc-536d-fitc.pdf

CAS Number

9007-83-4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CMV pp28 (CH19)
sc-69749 100 µg/mL

CMV pp28 (CH19)

Ask
View Details
Heteroclitin B
HY-N8622A Inquire

Heteroclitin B

Ask
View Details
DAP-3 (E-4):m-IgG Fc BP-HRP Bundle
sc-537929 1 Kit

DAP-3 (E-4):m-IgG Fc BP-HRP Bundle

Ask
View Details
Dicapthon
sc-257327 1 g

Dicapthon

Ask
View Details