What is the catalog number for Dityrosine Antibody, Clone 10A6?

The catalog number for Dityrosine Antibody, Clone 10A6 is SMC-521S.

What sizes are available for Dityrosine Antibody, Clone 10A6?

Dityrosine Antibody, Clone 10A6 is available in the following size(s): 12 µg.

Is Dityrosine Antibody, Clone 10A6 in stock?

Dityrosine Antibody, Clone 10A6 is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Dityrosine Antibody, Clone 10A6?

The safety data sheet for Dityrosine Antibody, Clone 10A6 is available here: https://www.stressmarq.com/wp-content/uploads/Antibody-MSDS.pdf.

Dityrosine Antibody, Clone 10A6

Mouse Anti-Dityrosine (DT) Monoclonal IgG1

Product Specifications

Background

Dityrosine is a stable, covalent cross-link formed between tyrosine residues in proteins under oxidative stress. It is generated by reactive oxygen species (ROS) such as hydroxyl radicals and catalyzed by peroxidases and UV radiation. As a biomarker of protein oxidation, dityrosine reflects cumulative oxidative damage in tissues. In the brain, elevated dityrosine levels are associated with protein aggregation, mitochondrial dysfunction, and neuroinflammation—features common to Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Monitoring dityrosine formation provides insight into oxidative stress burden and may aid in evaluating antioxidant therapies and disease progression in neurodegenerative research.

CAS Number

9007-83-4

Specifications

Specific for dityrosine modified proteins. Does not cross-react with 3,5-dibromotyrosine or bromotyrosine modified proteins.

Product Name Alternative

Dityrosine, Dityrosine (DT), DT, DY

Synonyms

Dityrosine Antibody, Clone 10A6

UNSPSC

12352203

UN Code

Non-hazardous

Hazard Statement

Non-hazardous

Host

Mouse

Species Reactivity

Species Independent

Immunogen

Synthetic Dityrosine conjugated to Keyhole Limpet Hemocyanin (KLH) .

Target

Dityrosine

Clonality

Monoclonal

Isotype

IgG1

Clone

10A6

Conjugation

Unconjugated

Type

Monoclonal

Applications

WB | ICC/IF | FACS | FCM | ELISA

Validated Applications

WB,ICC/IF,FACS,FCM,ELISA

Field of Research

Purification

Protein G Purified

Limit Of Detection

A 1:1000 dilution of SMC-521 was sufficient for detection of dityrosine in 1 µg of Dityrosine conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody.