Sycosterol A

Sycosterol A is a sterol-based α-synuclein (α-syn) inhibitor that targets α-synuclein aggregates and inhibits α-synuclein aggregation. Sycosterol A can be used in the study of anti-neurodegenerative diseases[1][2].

Product Specifications

UNSPSC

12352100

Target

α-synuclein

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sycosterol-a.html

Solubility

10 mM in DMSO

Smiles

[H][C@@]12[C@@H]([C@H]([C@@]([C@H](C)CCCC(C)COS(=O)(O)=O)([H])[C@]1(CC[C@]3([C@]2([C@@H](C[C@]4(C[C@@H](CC[C@@]43C)O)[H])O)O)[H])C)O)O

Molecular Formula

C27H48O9S

Molecular Weight

548.73

References & Citations

[1]Prebble DW, et al. Sycosterol A, an α-Synuclein Inhibitory Sterol from the Australian Ascidian Sycozoa cerebriformis. J Nat Prod. 2021;84 (12) :3039-3043.|[2]Gupta J, et al. Recent advances in natural products targeting α-synuclein aggregation or clearance in Parkinson's disease[J]. European Journal of Medicinal Chemistry Reports, 2023, 9: 100114.