SOAT-IN-1
SOAT-IN-1 (compound 40) is a potent and selective sodium-dependent organic anion transporter (SOAT) inhibitor with IC50 values of 1.6, 14.3 µM for SOAT, NTCP, respectively[1].
Product Specifications
CAS Number
898440-60-3
UNSPSC
12352211
Target
Na+/HCO3- Cotransporter
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/soat-in-1.html
Smiles
COC1=CC([N+]([O-])=O)=C(NC(C2=CC=CC=C2NS(=O)(C3=CC=C(Cl)C=C3)=O)=O)C=C1
Molecular Formula
C20H16ClN3O6S
Molecular Weight
461.88
References & Citations
[1]Wannowius M, et al. Structure-Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT. J Med Chem. 2024 Oct 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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