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SOAT-IN-1

SOAT-IN-1 (compound 40) is a potent and selective sodium-dependent organic anion transporter (SOAT) inhibitor with IC50 values of 1.6, 14.3 µM for SOAT, NTCP, respectively[1].

Product Specifications

CAS Number

[898440-60-3]

UNSPSC

12352211

Target

Na+/HCO3- Cotransporter

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/soat-in-1.html

Smiles

COC1=CC([N+]([O-])=O)=C(NC(C2=CC=CC=C2NS(=O)(C3=CC=C(Cl)C=C3)=O)=O)C=C1

Molecular Formula

C20H16ClN3O6S

Molecular Weight

461.88

References & Citations

[1]Wannowius M, et al. Structure-Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT. J Med Chem. 2024 Oct 17.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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