TSLP R, Mouse (HEK293, His)

Cytokine receptor-like factor 2 (Crlf2), also known as thymic stromal lymphopoietin (TSLP) receptor, is a receptor for TSLP. Crlf2 can forms a functional complex with TSLP and IL7RA, and overexpression of Crlf2 stimulates cell proliferation through activation of the JAK-STAT pathway. The expression of Crlf2 usually upregulates and mutated in populations of B-progenitor acute lymphoblastic leukemia (B-ALL)[1][2]. TSLP R Protein, Mouse (HEK293, His) is the recombinant mouse-derived TSLP R protein, expressed by HEK293 , with C-6*His labeled tag.

AAAVTSRGDV TVVCHDLETV EVTWGSGPDH HSANLSLEFR YGTGALQPCP RYFLSGAGVT SGCILPAARA GLLELALRDG GGAMVFKARQ RASAWLKPRP PWNVTLLWTP DGDVTVSWPA HSYLGLDYEV QHRESNDDED AWQTTSGPCC DLTVGGLDPA RCYDFRVRAS PRAAHYGLEA QPSEWTAVTR LSGAASAASC TASPAPSPAL APPL