WIZ degrader 2
WIZ degrader 2 (Compound 142) is a degrader for widely interspaced zinc finger motifs with an AC50 of 0.011 μM. WIZ degrader 2 induces the expression of fetal hemoglobin (HbF) with an EC50 of 0.038 μM. WIZ degrader 2 can be used in research about inherited blood disorders[1].
Product Specifications
CAS Number
2839552-69-9
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/wiz-degrader-2.html
Smiles
O=C(NC(CC1)=O)N1C(C=NN2C=C3)=C2C=C3C[C@H]4C[C@@H](N(CC4)CC5CCOCC5)C
Molecular Formula
C24H33N5O3
Molecular Weight
439.55
References & Citations
[1]BONAZZI S, et al., Pyrazolopyridine derivatives and uses thereof. WO2022195454A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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