BPAM344
BPAM344 is a kainate receptor (KAR) subunits GluK1b, GluK2a, and GluK3a positive allosteric modulator (PAM) [1].
Product Specifications
CAS Number
[1204572-55-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bpam344.html
Purity
99.66
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
FC1=CC=C(C2=C1)N(C3CC3)CNS2(=O)=O
Molecular Formula
C10H11FN2O2S
Molecular Weight
242.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Anja Probst Larsen, et al. Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors. Mol Pharmacol. 2017 Jun;91 (6) :576-585.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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