SSR128129E
SSR128129E is an orally available and allosteric FGFR inhibitor with an IC50 of 1.9 μM for FGFR1.
Product Specifications
CAS Number
[848318-25-2]
Product Name Alternative
SSR
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SSR128129E.html
Purity
99.85
Solubility
DMSO : ≥ 54 mg/mL
Smiles
O=C(O[Na])C1=CC(C(C2=C(C)C(OC)=C3C=CC=CN23)=O)=CC=C1N
Molecular Formula
C18H15N2NaO4
Molecular Weight
346.31
Precautions
H315, H319, H335
References & Citations
[1]Bono F, et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23 (4) :477-88.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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