SSR128129E
SSR128129E is an orally available and allosteric FGFR inhibitor with an IC50 of 1.9 μM for FGFR1.
Product Specifications
CAS Number
848318-25-2
Product Name Alternative
SSR
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SSR128129E.html
Purity
99.85
Solubility
DMSO : ≥ 54 mg/mL
Smiles
O=C(O[Na])C1=CC(C(C2=C(C)C(OC)=C3C=CC=CN23)=O)=CC=C1N
Molecular Formula
C18H15N2NaO4
Molecular Weight
346.31
Precautions
H315, H319, H335
References & Citations
[1]Bono F, et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23 (4) :477-88.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MR219467L3 10 µg
March5 (NM_001164336) Mouse Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
A00517-1-HRP 100 µg/Vial
Anti-Collagen II/COL2A1 Antibody Picoband® (HRP Conjugate)
Sign In for Pricing
View Details bsm-61661R-BF350-TR 20 µL
FADD Recombinant Antibody, AbBy Fluor™ 350 Conjugated
Sign In for Pricing
View Details