SSR128129E

SSR128129E is an orally available and allosteric FGFR inhibitor with an IC50 of 1.9 μM for FGFR1.

Product Specifications

CAS Number

[848318-25-2]

Product Name Alternative

SSR

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/SSR128129E.html

Purity

99.85

Solubility

DMSO : ≥ 54 mg/mL

Smiles

O=C(O[Na])C1=CC(C(C2=C(C)C(OC)=C3C=CC=CN23)=O)=CC=C1N

Molecular Formula

C18H15N2NaO4

Molecular Weight

346.31

Precautions

H315, H319, H335

References & Citations

[1]Bono F, et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23 (4) :477-88.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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