HSP90-IN-29
HSP90-IN-29 (Compound 13), a benzoxazole derivative, is a potent and selective HSP-90 inhibitor with an IC50 value of 30 nM. HSP90-IN-29 has antitumor activity[1].
Product Specifications
CAS Number
1012788-65-6
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsp90-in-29.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(C2=NOC3=C2C=C(NCCN4CCOCC4)C=C3)=C(C=C1O)O
Molecular Formula
C19H20ClN3O4
Molecular Weight
389.83
References & Citations
[1]Gopalsamy A, et al. Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90. J Med Chem. 2008 Feb 14;51 (3) :373-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90
Available Sizes
Frequently Asked Questions
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