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Firuglipel

Firuglipel (DS-8500a) is an orally available, potent and selective GPR119 agonist.

Product Specifications

CAS Number

1371591-51-3

Product Name Alternative

DS-8500a

UNSPSC

12352005

Target

GPR119

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Firuglipel.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC[C@H](C1=NC(C2=CC(F)=C(C(N[C@H](C)CO)=O)C=C2)=NO1)OC3=CC=C(C(C4CC4)=O)C=C3

Molecular Formula

C25H26FN3O5

Molecular Weight

467.49

References & Citations

[1]Matsumoto K, et al. DS-8500a, an Orally Available G Protein-Coupled Receptor 119 Agonist, Upregulates Glucagon-Like Peptide-1 and Enhances Glucose-Dependent Insulin Secretion and Improves Glucose Homeostasis in Type 2 Diabetic Rats. J Pharmacol Exp Ther. 2018 Dec;367 (3) :509-517.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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