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EAAC1 Antibody

Mouse Anti-Human EAAC1 Monoclonal IgG1

Product Specifications

Background

SLC1A1/EAAT3/EAAC1, a member of this transporter family, is expressed throughout the body, particularly in brain, intestine, liver, heart and kidney. Functional defects of the SLC1A1 gene are found in patients of dicarboxylicamino aciduria.

CAS Number

9007-83-4

Specifications

Detects ~60kDa.

Product Name Alternative

Excitatory amino-acid carrier 1 Antibody, excitatory amino acid transporter 3 Antibody, EAAT3 Antibody, Neuronal and epithelial glutamate transporter Antibody, Sodium-dependent glutamate/aspartate transporter 3 Antibody, solute carrier family 1 member 1 and Slc1a1 Antibody

Synonyms

EAAC1 Antibody, Clone N180/41

UNSPSC

12352203

Gene ID

6505

Swiss Prot

P43005

Accession Number

NP_004161.4

Cellular Locus

Membrane

Host

Mouse

Species Reactivity

Human,Rat

Immunogen

Fusion protein amino acids 1-524 (full length) of human EAAC1

Target

EAAT3

Clonality

Monoclonal

Isotype

IgG1

Clone

N180/41 (Formerly sold as S180-41)

Conjugation

Unconjugated

Validated Applications

WB,IP,ICC/IF

Purification

Protein G Purified

Limit Of Detection

5 µg of SMC-406 was sufficient for immunoprecipitation of EAAC1 from 50 µg of rat brain lysate.

Concentration

1 mg/ml

Dilution

WB (1:1000), ICC/IF (1:100);optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Smith C. P., et al., (1994) Genomics 20:335-336. 2. Kanai Y., and Hediger M. A. (1992) Nature 360:467-471.

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