PE-Labeled Human SLAMF7 / CRACC / CD319 Protein, His Tag (Site-specific conjugation)

PE-Labeled Human SLAMF7, His Tag (SL7-HP2H3) is produced via site-specific conjugation of PE to Human SLAMF7, His Tag under optimal conditions with a proprietary technology. Human SLAMF7, His Tag is expressed from human 293 cells (HEK293) . It contains AA Ser 23 - Met 226 (Accession # Q9NQ25-1) .

Product Specifications

Background

SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.6 kDa.

Accession Number

Q9NQ25-1

Expression Region

Ser 23 - Met 226

Host

HEK293

Target

SLAMF7

Conjugation

PE Labeled

Tag

C-10xHis

Source

Human

Applications

Evaluation of anti-SLAMF7 CAR expression by flow cytometry. Please note that this product is NOT compatible to streptavidin detection system.

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.