CGRP antagonist 1
Product Specifications
UNSPSC Description
CGRP antagonist 1 (compound 21) is a highly potent CGRP receptor antagonist with a Ki and an IC50 of 1.7 nM and 5.7 nM, respectively[1].
Target Antigen
CGRP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC2=C(C[C@@]3(C4=CC=CN=C4NC3=O)C2)C=C1)CN5C(C6(CCOCC6)C7=C5C=CC=C7)=O
Molecular Weight
494.54
References & Citations
[1]Stump CA, et al. The discovery of highly potent CGRP receptor antagonists. Bioorg Med Chem Lett. 2009 Jan 1;19(1):214-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112262/CGRP-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112262/
Clinical Information
No Development Reported
CAS Number
1123757-49-2
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Human Vacuolar fusion protein CCZ1 homolog (CCZ1)
Recombinant Human Vacuolar fusion protein CCZ1 homolog (CCZ1)
Recombinant Human Vacuolar fusion protein CCZ1 homolog (CCZ1)
Recombinant Human Vacuolar fusion protein CCZ1 homolog (CCZ1)
Recombinant Human Vacuolar fusion protein CCZ1 homolog (CCZ1)