SSR504734 (free base)
Product Specifications
UNSPSC Description
SSR504734 free base is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38?nM, respectively). SSR504734 free base shows anti-schizophrenia, anti-anxiety and anti-depression activities[1].
Target Antigen
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ssr504734-free-base.html
Smiles
O=C(C1=CC=CC(C(F)(F)F)=C1Cl)NC[C@H]2N(CCCC2)C3=CC=CC=C3
Molecular Weight
396.83
References & Citations
[1]Ronan Depoortère, et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology. 2005 Nov;30(11):1963-85.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114895/SSR504734-free-base-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114895/
Clinical Information
No Development Reported
CAS Number
742693-38-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
