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MAP2 (Phospho-Thr1616) rabbit pAb

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],

Product Specifications

Background

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

Synonyms

Microtubule-associated protein 2 (MAP-2)

Gene ID

4133

UniProt

P11137

Cellular Locus

Cytoplasm, cytoskeleton. Cell projection, dendrite.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human MAP2 (Phospho-Thr1616)

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, WB

Validated Applications

IHC,IF,WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-200, WB 1:500-2000

Molecular Weight

280kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES15040-1.pdf

Observed Molecular Weight

280 kD

Subcellular Location

Cytoplasm, cytoskeleton . Cell projection, dendrite .

Other Product Names

Microtubule-associated protein 2 (MAP-2)

Gene ID (Human)

4133

SwissProt (Human)

P11137

Available Sizes

Curated Selection

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