Desmethyl Celecoxib

Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%[1].

Product Specifications

CAS Number

[170569-87-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/desmethyl-celecoxib.html

Purity

99.42

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC(F)(C1=NN(C(C2=CC=CC=C2)=C1)C3=CC=C(C=C3)S(=O)(N)=O)F

Molecular Formula

C16H12F3N3O2S

Molecular Weight

367.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Vinay Kumar Sthalam, et al. An Integrated Continuous Flow Micro-Total Ultrafast Process System (μ-TUFPS) for the Synthesis of Celecoxib and Other Cyclooxygenase Inhibitors. RETURN TO ISSUEPREVARTICLENEXT