HEK293/Human GLP-1R Stable Cell Line (Low Expression)

HEK293/Human GLP-1R Stable Cell Line (Low Expression) is expressed from Human HEK293.

Product Specifications

Background

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.

Host

HEK293

Origin Species

Human

Target

GLP1R

Applications

• Useful for cell-based GLP-1R binding assay • Screen for human GLP-1R agonists based on cAMP accumulation assay

Format

Liquid

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

Frozen in liquid nitrogen

Package Size

1Vial*2

Host or Source

HEK293

Species