ML240
ML240 is a potent p97 inhibitor, inhibiting p97 ATPase with IC50 value of 100 nM.
Product Specifications
CAS Number
1346527-98-7
UNSPSC
12352005
Hazard Statement
H302
Target
P97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ML240.html
Purity
99.87
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
COC1=CC=CC2=C(NCC3=CC=CC=C3)N=C(N4C(N)=NC5=CC=CC=C45)N=C12
Molecular Formula
C23H20N6O
Molecular Weight
396.44
Precautions
H302
References & Citations
[1]Chou TF et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem, 2013 Feb, 8 (2) :297-312.|[2]Chou TF, et al. Selective, reversible inhibitors of the AAA ATPase p97. Probe Reports from the NIH Molecular Libraries Program. April 14, 2011.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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