ML240

ML240 is a potent p97 inhibitor, inhibiting p97 ATPase with IC50 value of 100 nM.

Product Specifications

CAS Number

[1346527-98-7]

UNSPSC

12352005

Hazard Statement

H302

Target

P97

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ML240.html

Purity

99.87

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

COC1=CC=CC2=C(NCC3=CC=CC=C3)N=C(N4C(N)=NC5=CC=CC=C45)N=C12

Molecular Formula

C23H20N6O

Molecular Weight

396.44

Precautions

H302

References & Citations

[1]Chou TF et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem, 2013 Feb, 8 (2) :297-312.|[2]Chou TF, et al. Selective, reversible inhibitors of the AAA ATPase p97. Probe Reports from the NIH Molecular Libraries Program. April 14, 2011.