PGPC (Highy Pure)

<strong>PGPC (Highy Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2017954_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 609.729_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen S, Gao JJ, Liu YJ, Mo ZW, Wu FY, Hu ZJ, Peng YM, Zhang XQ, Ma ZS, Liu ZL, Yan JY, Ou ZJ, Li Y, Ou JS. The oxidized phospholipid PGPC impairs endothelial function by promoting endothelial cell ferroptosis via FABP3 J Lipid Res. 2024 Feb;65(2):100499._x000D_ 2: Zhivaki D, Kennedy SN, Park J, Boriello F, Devant P, Cao A, Bahleda KM, Murphy S, McCabe C, Evavold CL, Chapman KL, Zanoni I, Ashenberg O, Xavier RJ, Kagan JC. Correction of age-associated defects in dendritic cells enables CD4(+) T cells to eradicate tumors Cell. 2024 Jul 25;187(15):3888-3903.e18._x000D_ 3: Ranganathan R, Alshammri I, Peric M. Lipid Organization in Mixed Lipid Membranes Driven by Intrinsic Curvature Difference Biophys J. 2020 Apr 21;118(8):1830-1837._x000D_ 4: Fruhwirth GO, Moumtzi A, Loidl A, Ingolic E, Hermetter A. The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells Biochim Biophys Acta. 2006 Sep;1761(9):1060-9._x000D_ 5: Singh J, Ranganathan R. Mixing of oxidized and bilayer phospholipids Biochim Biophys Acta. 2015 Jul;1848(7):1472-80._x000D_ 6: Stemmer U, Dunai ZA, Koller D, Pürstinger G, Zenzmaier E, Deigner HP, Aflaki E, Kratky D, Hermetter A. Toxicity of oxidized phospholipids in cultured macrophages Lipids Health Dis. 2012 Sep 7;11:110._x000D_ 7: Koller D, Hackl H, Bogner-Strauß JG, Hermetter A. Effects of oxidized phospholipids on gene expression in RAW 264.7 macrophages: a microarray study PLoS One. 2014 Oct 21;9(10):e110486._x000D_ 8: Karki P, Zhang CO, Promnares K, Li Y, Ke Y, Birukova AA, Birukov KG. Truncated oxidized phospholipids exacerbate endothelial dysfunction and lung injury caused by bacterial pathogens Cell Signal. 2023 Sep;109:110804._x000D_ 9: Ayee MAA, LeMaster E, Shentu TP, Singh DK, Barbera N, Soni D, Tiruppathi C, Subbaiah PV, Berdyshev E, Bronova I, Cho M, Akpa BS, Levitan I. Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids Biophys J. 2017 Jan 24;112(2):325-338._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/4831638">10: Patel DJ. Peptide antibiotic-dinucleotide interactions. Nuclear magnetic resonance investigations of complex formation between actinomycin D and d-pGpC in aqueous solution Biochemistry. 1974 May 21;13(11):2388-95. </a>_x000D_ _x000D_ <strong>Products Related to PGPC (Highy Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Lipids/"> Lipids</a>