CAY10698

CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2[1].

Product Specifications

CAS Number

[684236-01-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Lipoxygenase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cay10698.html

Purity

99.28

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=C(C(CNC2=CC=C(C=C2)S(NC3=NC=CS3)(=O)=O)=CC=C1)O

Molecular Formula

C17H17N3O4S2

Molecular Weight

391.46

Precautions

H302, H315, H319, H335

References & Citations

[1]David J. Maloney, et al. 4- ((2-hydroxy-3-methoxybenzyl) amino) benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase.