Eprazinone
Eprazinone can enhance lung function and arterial oxygen levels and can be used in the study of chronic bronchitis. Higher doses of eprazinone increased phospholipid levels and decreased neutral lipid content in bronchoalveolar lavage (BAL) fluid, but had no effect on protein and cell levels in BAL. Eprazinone dose-dependently reduced short-circuit current (Isc), primarily by reducing chloride secretion at lower concentrations and affecting sodium and chloride transport at higher doses. Eprazinone may exert its anti-inflammatory effects by regulating BAL lipid composition and airway ion transport[1].
Product Specifications
CAS Number
10402-90-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/eprazinone.html
Smiles
O=C(C1=CC=CC=C1)C(C)CN2CCN(CC(OCC)C3=CC=CC=C3)CC2
Molecular Formula
C24H32N2O2
Molecular Weight
380.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Thrall RS, et al. Eprazinone alters lung lavage lipid levels and transtracheal ion transport. Exp Lung Res. 1992 May-Jun;18 (3) :409-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Explore Other Products
Browse additional items from our catalog
Cytokeratin 6 Recombinant Rabbit mAb, PerCP-Cy5.5 conjugated
NR4A3 (Nuclear Receptor Subfamily 4 Group A Member 3, Mitogen-induced Nuclear Orphan Receptor, Neuron-derived Orphan Receptor 1, Nuclear Hormone Receptor NOR-1, CHN, CSMF, MINOR, NOR1, TEC)
MPST (3-Mercaptopyruvate Sulfurtransferase, Mercaptopyruvate Sulfurtransferase)