Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Glasdegib

Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM[1].

Product Specifications

CAS Number

1095173-27-5

Product Name Alternative

PF-04449913

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Smo

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PF-04449913.html

Purity

99.65

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2

Molecular Formula

C21H22N6O

Molecular Weight

374.44

Precautions

H315, H319, H320

References & Citations

[1]Sadarangani A, et al. GLI2 inhibition abrogates human leukemia stem cell dormancy. J Transl Med. 2015 Mar 21;13:98.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human FGF17 activation kit by CRISPRa
GA105866 1 Kit

Human FGF17 activation kit by CRISPRa

Sign In for Pricing
View Details
Nav1.5 (SCN5A) Mouse Monoclonal Antibody [Clone ID: OTI5E9]
CF815385 100 µg

Nav1.5 (SCN5A) Mouse Monoclonal Antibody [Clone ID: OTI5E9]

Sign In for Pricing
View Details
Colloidal Gold Conjugated Griffonia simplicifolia Lectin -GS-I-B4 -,  5nm
GP-2401-B-5 1 mL

Colloidal Gold Conjugated Griffonia simplicifolia Lectin -GS-I-B4 -, 5nm

Sign In for Pricing
View Details
Frozen Tissue Blocks, Ovary: right
CB501068 1 Block

Frozen Tissue Blocks, Ovary: right

Sign In for Pricing
View Details
Colloidal Gold Conjugated Monoclonal Antibody to Herpes Simplex I,  15nm
GM-15-15 1 mL

Colloidal Gold Conjugated Monoclonal Antibody to Herpes Simplex I, 15nm

Sign In for Pricing
View Details
Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine
TRC-B230760-500MG 500 mg

Benzyl-8-azabicyclo[3.2.1]octan-3-exo-amine

Sign In for Pricing
View Details