Tubulin polymerization-IN-65
Tubulin polymerization-IN-65 is a tubulin polymerisation inhibitor with a broad spectrum cytotoxic. Tubulin polymerization-IN-65 induces G2 + M cell cycle arrest[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-65.html
Smiles
O=C1NC(/C=C/C2=CC=CC=C2OC)=NC3=CC=CC=C31
Molecular Formula
C17H14N2O2
Molecular Weight
278.31
References & Citations
[1]Nicholas S O'Brien, et al. 2,3-Dihydroquinazolin-4 (1 H) -ones and quinazolin-4 (3 H) -ones as broad-spectrum cytotoxic agents and their impact on tubulin polymerisation. RSC Med Chem. 2024 Mar 6;15 (5) :1686-1708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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