Verinurad
Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC50 of 25 nM[1].
Product Specifications
CAS Number
1352792-74-5
Product Name Alternative
RDEA3170
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Verinurad.html
Purity
99.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(SC1=C(C2=C3C=CC=CC3=C(C#N)C=C2)C=NC=C1)C(O)=O
Molecular Formula
C20H16N2O2S
Molecular Weight
348.42
Precautions
H302, H312, H332
References & Citations
[1]Tan PK, et al. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Sci Rep. 2017 Apr 6;7 (1) :665.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
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