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Verinurad

Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC50 of 25 nM[1].

Product Specifications

CAS Number

[1352792-74-5]

Product Name Alternative

RDEA3170

UNSPSC

12352005

Hazard Statement

H302, H312, H332

Target

URAT1

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Verinurad.html

Purity

99.18

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C)(SC1=C(C2=C3C=CC=CC3=C(C#N)C=C2)C=NC=C1)C(O)=O

Molecular Formula

C20H16N2O2S

Molecular Weight

348.42

Precautions

H302, H312, H332

References & Citations

[1]Tan PK, et al. Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout. Sci Rep. 2017 Apr 6;7 (1) :665.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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