Cemdisiran
Cemdisiran is an N-acetylgalactosamine (GalNAc) conjugated siRNA for the research of complement-mediated diseases by suppressing liver production of complement 5 (C5) protein.
Product Specifications
CAS Number
1639264-46-2
Product Name Alternative
ALN-CC5
UNSPSC
12352208
Target
Complement System; Small Interfering RNA (siRNA)
Type
Oligonucleotides
Related Pathways
Epigenetics; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cemdisiran.html
Purity
95.24
Solubility
H2O : ≥ 20 mg/mL
Smiles
[Cemdisiran]
Molecular Formula
C542H711F17N169O330P45S6
Molecular Weight
16782.53
References & Citations
[1]Badri P, Jiang X, Borodovsky A, et al. Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria. Clin Pharmacokinet. 2021;60 (3) :365-378.|[2]Prajakta Badri, et al. Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria. Clin Pharmacokinet. 2021;60 (3) :365-378.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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