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MERS-CoV Spike/S RBD (Biotinylated, sf9, His)

The SARS-CoV Spike glycoprotein (S) has three subunits S1, S2' and S2 through alternative splicing. The engagement of the MERS-CoV spike protein S1 with CD26 (also known as dipeptidyl peptidase 4, DPP4) mediates viral attachment to host cells and virusell fusion, thereby initiating infection. S2 mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein and S2' is unmasked following S2 cleavage occurring upon virus endocytosis. MERS-CoV Spike/S Protein RBD (Biotinylated, sf9, His) is the recombinant Virus-derived MERS-CoV Spike/S protein RBD, expressed by Sf9 insect cells , with C-His labeled tag.

Product Specifications

Product Name Alternative

MERS-CoV Spike/S Protein RBD (Biotinylated, sf9, His), Virus, Sf9 insect cells

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/mers-cov-spike-protein-rbd-biotinylated-sf9-his.html

Molecular Formula

14254594 (Gene_ID) K0BRG7/AFS88936.1 (E367-Y606) (Accession)

Molecular Weight

Approximately 27.7 kDa

References & Citations

[1]Lu G, et al. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature. 2013 Aug 8;500 (7461) :227-31.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

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