Phospho-PI3K p85 (Y467) + PI3K p55 (Y199) Recombinant Rabbit Monoclonal Antibody [PSH01-38]
Selected Variant
HA721672
Size: 100 µL
Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
PIK3R1, GRB1
Swiss Prot
P27986 Human, P26450 Mouse
Cellular Locus
Cell-cell junction, cis-Golgi network, cytoplasm, cytosol, membrane, nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human PIK3R1 aa 451-500 / 724.
Isotype
IgG
Clone
PSH01-38
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 84 kDa/55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
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