(S) -Alaproclate (hydrochloride)
(S) -Alaproclate ((S) -A03) hydrochloride is a potent selective serotonin reuptake inhibitor (SSRI), which is used as an antidepressant agent. (S) -Alaproclate (hydrochloride) also produces a potent block of N-methyl-d-aspartate (NMDA) receptor currents in hippocampal neurons (IC50=1.1 μM) with a potent blocker of K+ currents[1].
Product Specifications
CAS Number
57469-92-8
Product Name Alternative
(S) -GEA 654 (hydrochloride) ; (S) -A03 (hydrochloride)
UNSPSC
12352005
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-alaproclate-hydrochloride.html
Smiles
N[C@@H](C)C(OC(C)(C)CC1=CC=C(Cl)C=C1)=O.Cl
Molecular Formula
C13H19Cl2NO2
Molecular Weight
292.20
References & Citations
[1]Svensson BE, et al. Alaproclate effects on voltage-dependent K+ channels and NMDA receptors: studies in cultured rat hippocampal neurons and fibroblast cells transformed with Kv1.2 K+ channel cDNA. Neuropharmacology. 1994 Jun;33 (6) :795-804.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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