N- (Azido-PEG3) -N- (PEG2-amine) -PEG3-acid
N- (Azido-PEG3) -N- (PEG2-amine) -PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N- (Azido-PEG3) -N- (PEG2-amine) -PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[2183440-70-0]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-azido-peg3-n-peg2-amine-peg3-acid.html
Purity
99.58
Solubility
10 mM in DMSO
Smiles
O=C(O)CCOCCOCCOCCN(C(CCOCCOCCN)=O)CCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C24H47N5O11
Molecular Weight
581.66
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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