BPI-15086
BPI-15086 an orally active, potent, irreversible mutant-selective inhibitor of both EGFR and T790M resistance mutations tyrosine kinase. BPI-15086 can be used for the research of non-small-cell lung cancer[1].
Product Specifications
CAS Number
1644502-33-9
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bpi-15086.html
Smiles
ClC(C(NC1=CC=CC=C1C(C(N(C)C)=O)=O)=N2)=CN=C2NC3=CC(NC(C=C)=O)=C(N4CCN(C)CC4)C=C3OC
Molecular Formula
C29H33ClN8O4
Molecular Weight
593.08
References & Citations
[1]Wang S, et al. Determination of BPI15086 and its metabolite in human plasma by ultra-high performance liquid chromatography-MS/MS and its application to a pharmacokinetic study. Bioanalysis. 2019 Apr;11 (8) :773-784.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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