Picrinine
Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1].
Product Specifications
CAS Number
[4684-32-6]
UNSPSC
12352005
Target
Lipoxygenase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/picrinine.html
Purity
99.33
Solubility
DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@@]1([H])[C@@](C(C=CC=C2)=C2N3)(C[C@]4([H])O5)[C@@]35[C@]6([H])C[C@@]1([H])/C(CN64)=C\C)OC
Molecular Formula
C20H22N2O3
Molecular Weight
338.40
References & Citations
[1]Smith JM, et, al. Total synthesis of the akuammiline alkaloid picrinine. J Am Chem Soc. 2014 Mar 26;136 (12) :4504-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX
Available Sizes
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