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Picrinine

Product Specifications

UNSPSC Description

Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1].

Target Antigen

Lipoxygenase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/picrinine.html

Purity

99.33

Solubility

DMSO : 33.33 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C([C@@]1([H])[C@@](C(C=CC=C2)=C2N3)(C[C@]4([H])O5)[C@@]35[C@]6([H])C[C@@]1([H])/C(CN64)=C\C)OC

Molecular Weight

338.40

References & Citations

[1]Smith JM, et, al. Total synthesis of the akuammiline alkaloid picrinine. J Am Chem Soc. 2014 Mar 26;136(12):4504-7.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N2074/Picrinine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N2074/Picrinine-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

4684-32-6

Available Sizes

Curated Selection

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