2-Aminofluorene

2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[1][4].

Product Specifications

CAS Number

[153-78-6]

UNSPSC

12352005

Hazard Statement

H351, H411

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-aminofluorene.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=CC(CC2=C3C=CC=C2)=C3C=C1

Molecular Formula

C13H11N

Molecular Weight

181.24

Precautions

H351, H411

References & Citations

[1]Heflich RH, et al. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat Res. 1994 Oct;318 (2) :73-114. |[2]Kim BS, et al. Immunosuppressive effects of 2-acetylaminofluorene and 2-aminofluorene on murine splenocytes culture. Drug Chem Toxicol. 1989 Sep-Dec;12 (3-4) :297-311. |[3]Levy GN, et al. 2-Aminofluorene-DNA adduct formation in acetylator congenic mouse lines. Carcinogenesis. 1989 Apr;10 (4) :705-9.