PF-1367550
PF-1367550 is a pan-JAK inhibitor. PF-1367550 can decrease the levels of release of CXCL9, CXCL10 and CXCL11 from primary airway epithelial cells[1].
Product Specifications
CAS Number
319461-60-4
UNSPSC
12352005
Target
JAK
Type
Natural Products
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pf-1367550.html
Smiles
OC1=CC(CC)=C(C2=CC3=C(C(C4=NC5=C(N4)C=CC=C5)=NN3)C=C2)C=C1
Molecular Formula
C22H18N4O
Molecular Weight
354.40
References & Citations
[1]Fenwick PS, et, al. Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells. PLoS One. 2015 Jun 19;10 (6) :e0128757.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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