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PF-1367550

PF-1367550 is a pan-JAK inhibitor. PF-1367550 can decrease the levels of release of CXCL9, CXCL10 and CXCL11 from primary airway epithelial cells[1].

Product Specifications

CAS Number

319461-60-4

UNSPSC

12352005

Target

JAK

Type

Natural Products

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pf-1367550.html

Smiles

OC1=CC(CC)=C(C2=CC3=C(C(C4=NC5=C(N4)C=CC=C5)=NN3)C=C2)C=C1

Molecular Formula

C22H18N4O

Molecular Weight

354.40

References & Citations

[1]Fenwick PS, et, al. Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells. PLoS One. 2015 Jun 19;10 (6) :e0128757.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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