Ethacridine
Ethacridine is a poly (ADP-ribose) glycohydrolase (PARG) inhibitor and an activator of the transcriptional coactivator. Ethacridine induces thyroid cancer cells apoptosis and promotes differentiation in thyroid follicular cells[1].
Product Specifications
CAS Number
[442-16-0]
UNSPSC
12352005
Hazard Statement
H302
Target
Apoptosis; Poly (ADP-ribose) Glycohydrolase (PARG)
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ethacridine.html
Purity
90.0
Smiles
CCOC1=CC2=C(C3=CC=C(C=C3N=C2C=C1)N)N
Molecular Formula
C15H15N3O
Molecular Weight
253.30
Precautions
H302
References & Citations
[1]Huang TS, et al. Ethacridine Induces Apoptosis and Differentiation in Thyroid Cancer Cells In Vitro. Anticancer Res. 2019 Aug;39 (8) :4095-4100.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
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