VEGFR-2/AKT-IN-1
Product Specifications
UNSPSC Description
VEGFR-2/AKT-IN-1 (compound 17) is a dual inhibitor of VEGFR-2 and AKT, with the IC50s of 0.164 μM and 0.452 μM, respectively. VEGFR-2/AKT-IN-1 has antitumor activity[1].
Target Antigen
Akt; VEGFR
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-akt-in-1.html
Smiles
NC1=C(C2=NN=C(NC(C3=CC=CC=C3)=O)S2)SC4=C1C5=NC(N)=NN5C=N4
Molecular Weight
409.45
References & Citations
[1]Heba K Abd El-Mawgoud, et al. Design, synthesis and cytotoxic evaluation of new thieno[2,3-d]pyrimidine analogues as VEGFR-2/AKT dual inhibitors, apoptosis and autophagy inducers. Bioorg Chem. 2024 Sep:150:107622.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161861/VEGFR-2-AKT-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161861/
Clinical Information
No Development Reported
Curated Selection
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