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5,5'-Dinitro BAPTA AM

Product Specifications

UNSPSC Description

5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].

Target Antigen

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-5-dinitro-bapta-am.html

Solubility

10 mM in DMSO

Smiles

O=[N+](C1=CC=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCCOC2=CC([N+]([O-])=O)=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C1)[O-]

Molecular Weight

854.68

References & Citations

[1]Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75(1):99-109.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-D1643/5-5-Dinitro-BAPTA-AM-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-D1643/

Clinical Information

No Development Reported

CAS Number

172646-47-8

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