5,5'-Dinitro BAPTA AM
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
Product Specifications
CAS Number
[172646-47-8]
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-5-dinitro-bapta-am.html
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=CC=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCCOC2=CC([N+]([O-])=O)=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C1)[O-]
Molecular Formula
C34H38N4O22
Molecular Weight
854.68
References & Citations
[1]Ouanounou A, et al. Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission at hippocampal CA1 neurons. Neuroscience. 1996 Nov;75 (1) :99-109.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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