Z-VA-DL-D-FMK
Selected Variant
HY-16658C-01
Size: 1 mg
Z-VA-DL-D-FMK (Z-VA-DL-D (OH) -FMK) is an inhibitor for caspase[1]. Z-VA-DL-D-FMK binds irreversibly to caspases, increases the sensitivity of TNF-α, and activates HIV replication in infected T cell ACH-2[1].
Product Specifications
CAS Number
220644-02-0
Product Name Alternative
Z-VA-DL-D (OH) -FMK
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/z-va-dl-d-fmk.html
Smiles
O=C(CF)C(NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)CC(O)=O
Molecular Formula
C21H28FN3O7
Molecular Weight
453.46
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Scheller C, et al., Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95. J Biol Chem. 2002 May 3;277 (18) :15459-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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