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EMAL4 rabbit pAb

This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015],

Product Specifications

Background

This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]

Gene ID

27436

UniProt

Q9HC35

Cellular Locus

Cytoplasm, cytoskeleton. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center. Midbody. Localizes to microtubules (MTs) during interphase with a significantly reduced affinity for MTs during mitosis..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human EMAL4 AA range: 398-448

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1: 500-2000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES16756-1.pdf

Subcellular Location

Cytoplasm, cytoskeleton . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, microtubule organizing center . Midbody . Localizes to microtubules (MTs) during interphase with a significantly reduced affinity for MTs during mitosis. .

Gene ID (Human)

27436

SwissProt (Human)

Q9HC35

Available Sizes

Curated Selection

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